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Fig. 7 | Biological Research

Fig. 7

From: Focal ischemic stroke modifies microglia-derived exosomal miRNAs: potential role of mir-212-5p in neuronal protection and functional recovery

Fig. 7

MiR-212-5p promoted dendritic spine formation and dendritic growth at 7 days following MCAO/R. A Representative Golgi-Cox-stained photomicrograph of brains from rats subjected to MCAO/R. Scale bar = 50 μm and 20 μm. B The apical dendritic intersections were counted at increasing distances from the centre of the soma. C The total number of intersections in the apical dendrites. D The basal dendritic intersections were counted at increasing distances from the centre of the soma. E The total number of intersections for the basal dendrites. F The total number of branches of apical dendrites. G The total number of branches of basal dendrites. H Graphs of dendritic spines on apical dendrites. Scale bar = 10 μm. I Density of dendritic spines along apical dendrites. J Graphs of dendritic spines on basal dendrites. Scale bar = 10 μm. K Density of dendritic spines along basal dendrites. The data are presented as the means ± SEM (n = 3 per group). *P < 0.05 and **P < 0.01 compared with the sham group, #P < 0.05 and ##P < 0.01 compared with the MCAO/R group

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