Fig. 3

Treatment with agomir-212-5p decreased neurological deficits and improved locomotor activity 7 days after MCAO/R. A The flow chart of the experiment. B Schematic of the scoring criteria for the foot fault test. C Foot fault test results. D Neurological deficit scores were evaluated using the Zea Longa 5-point scheme. E Illustrative waveforms of motor evoked potential (MEP) for each group. F The amplitude of MEP for each group. G The latency of MEP for each group. n = 6 per group. H Schematic representation of the CatWalk gait analysis. I Running duration (s). J Average running speed (cm/s). K Right forelimb stride length (cm). L Right hindlimb stride length (cm). The data are presented as the means ± SEM (n = 8 per group). M Results of functional connectivity analysis among four groups. *P < 0.05 and **P < 0.01 compared with the sham group, ^#P < 0.05 and ^##P < 0.01 compared with the MCAO/R group