Fig. 1

aSNPs filtering and analysis workflow for each ancestry group. The figure displays aSNPs analysis workflow for non-Finnish Europeans, Finns, and East Asians. The 389 144 aSNPs identified in all non-African populations from 1000 Genomes project phase 3, were filtered and analysed for each ancestry group. aSNP Neandertal introgressed SNP. ¹aSNPs that showed an association P-value < 0.05 in PanScan, PanC4 and in the two datasets combined. aSNPs with a P < 0.05 in PanScan (7850), PanC4 (8141), and the combined datasets (8718). ²aSNPs with a P-value < 0.05 and an identical direction of the effect in all the three GWASs included in JaPAN