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Fig. 5 | Biological Research

Fig. 5

From: Polar microalgae extracts protect human HaCaT keratinocytes from damaging stimuli and ameliorate psoriatic skin inflammation in mice

Fig. 5

The effects of polar microalgae extracts on the transcriptome of HaCaT cells treated with M5 cytokines. (a) Multidimensional scaling analysis of gene expression data. In the control group, the HaCaT cells were cultured without overnight pretreatment with polar microalgae extracts followed by 18 h of M5 cytokine stimulation. (b) Gene ontology enrichment in M5 cytokine-stimulated HaCaT cells that were pretreated with or without KSF0041 by gene set enrichment analysis. (c) Selected gene sets that were differentially expressed between HaCaT cells pretreated with KSF0041 and stimulated with M5 cytokines and HaCaT cells only stimulated with M5 cytokines (adjusted p < 0.05). Heat map showing the log2 fold changes to the geometric mean of fragments per kilobase of exons per million fragments mapped + 0.01. The data were generated from a single experiment

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Biological Research

ISSN: 0717-6287

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