Fig. 8

EA regulated synaptic plasticity by modulating NMDAR channel activity in the EC-HIP CA1 circuit in 2-VO rats

(A) Representative EPSC traces in bicuculline (50 µM) at -60 mV and + 40 mV in each group. (B) Summary graph of the NMDAR/AMPAR ratio. (C) Escape latency of rats during training. (D) Passes over the missing platform. (E) Time spent in the target quadrant. *VS Sham group, P<0.05,**, P<0.01. #,VS 2-VO group, P<0.05. ^,VS EA group, P<0.05. (B. One-way ANOVA, followed by Tukey’s post hoc test, n = 6 sections from 3 rats/group, C. Repeated Measures Analysis of Variance, RM ANOVA, followed by Tukey’s post hoc test, D-E. One-way ANOVA, followed by a Tukey’s post hoc test, n = 10 rats/group, Data represent the mean ± SD)