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Fig. 6 | Biological Research

Fig. 6

From: Electroacupuncture protective effects after cerebral ischemia are mediated through miR-219a inhibition

Fig. 6

EA enhanced the synaptic plasticity of the EC-HIP CA1 circuit by miR-219a in 2-VO rats

(A) Timeline of the experiment. (B) and (C) Relative expression of miR-219a in the CA1 region of the HIP and in the EC. (D) rVAA-CMV-Dio-Mir-219a-mCherry-pA injection sites in the entorhinal cortex and rAVV-hSyn-GFP-2 A-CRE-WPRE-PA injection sites in the CA1 region of the hippocampus. (E) Green fluorescence and red fluorescence magnified detail. *VS Sham group, P<0.05, **, P<0.01. #,VS 2-VO group, P<0.05. ^, VS EA group, P<0.05.(C. One-way ANOVA, followed by a Tukey’s post hoc test, n = 3 rats/ group, Data represent the mean ± SD)

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