Table 1 Features and chromatin status of genomic sequences containing VDAC pseudogenes, from UCSC Genome Browser GRCh38/hg38
From: Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia
Name | Entrez ID | Genomic coordinates | Regulatory build | |||
|---|---|---|---|---|---|---|
Location | Size (bp) | Strand | 5'-Flanking region | 3'-Flanking region | ||
(a) | ||||||
 VDAC1P1 | 642585 | chrX:80184923–80186706 | 1784 |  +  | Heterochromatin | Insulator and weak enhancer |
 VDAC1P2 | 10064 | chrX:49396238–49397962 | 1725 | − | Heterochromatin | |
 VDAC1P3 | 100310838 | chrX:91236801–91238513 | 1713 | − | Weak enhancers, weak and active promoter (overlapping intronic region of PCDH11X gene) | |
 VDAC1P4 | 7418 | chr1:180403931–180405937 | 2007 |  +  | weak and strong enhancers, weak transcriptional elongation, weak promoter (overlapping intronic region of ACBD6 gene) | |
 VDAC1P5 | 10187 | chr12:55195669–55197407 | 1739 | − | Heterochromatin | |
 VDAC1P6 | 359800 | chrY:5074406–5076119 | 1714 | − | Heterochromatin (overlapping intronic region of PCDH11Y gene) | |
 VDAC1P7 | 100310839 | chr3:77365047–77366767 | 1721 | − | Insulator | Heterochromatin (overlapping intronic region of ROBO2 gene) |
 VDAC1P8a | 100310840 | chr6:143811645–143813335 | 1691 |  +  | Weak enhancer, weak transcriptional elongation (proximity to PEX3 gene) | Weak and strong enhancer, weak transcriptional elongation (proximity to FUCA2 gene) |
 VDAC1P9 | 391106 | chr1:157693990–157694816 | 827 | − | Heterochromatin | Weak enhancer, weak transcriptional elongation |
 VDAC1P10 | 643536 | chr1:215549841–215551581 | 1741 |  +  | Flanking heterochromatin and weak enhancers inside gene body | |
 VDAC1P11 | 100310841 | chr9:97048814–97050837 | 2024 | − | Weak transcriptional elongation, weak and strong enhancer (overlapping intronic region of ZNF169 gene) | |
 VDAC1P12 | 100874289 | chr13:34656914–34657447 | 534 | − | Heterochromatin | |
 VDAC1P13 | 100420568 | chr2:42690279–42691137 | 859 | − | Weak enhancers, weak transcriptional elongation (overlapping intronic region of KCNG3 gene) | |
(b) | ||||||
 VDAC2P1 | 54015 | chr21:17466509–17467792 | 1284 | − | Heterochromatin (overlapping LINC00478 gene) | |
 VDAC2P2 | 643996 | chr12:9188920–9190119 | 1200 | − | Heterochromatin | |
 VDAC2P3 | 401959 | chr1:118182962–118184349 | 1388 | − | Insulator, weak enhancer, heterochromatin | Weak transcriptional elongation, polycomb repressed, heterochromatin |
 VDAC2P4 | 100420574 | chr2:135554739–135555449 | 711 |  +  | Heterochromatin, insulator, Polycomb repressor | |
(c) | ||||||
 VDAC3P1 | 341965 | chr14:100430801–100431912 | 1112 |  +  | Weak transcriptional elongation, heterochromatin, Polyocomb repressed | Weak enhancer, heterochromatin, Polyocomb repressed |