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Fig. 6 | Biological Research

Fig. 6

From: Acupuncture regulates the apoptosis of ovarian granulosa cells in polycystic ovarian syndrome-related abnormal follicular development through LncMEG3-mediated inhibition of miR-21-3p

Fig. 6

Acupuncture ameliorates abnormal sex hormone levels and ovarian histopathological changes in PCOS rats. A Experimental strategy for acupuncture intervention; B HE staining was used to observe pathological changes in the ovaries of PCOS rats after the acupuncture intervention (scale bar = 200 μm); C Number of mature follicles in the ovarian tissue of PCOS rats after the acupuncture intervention; D Number of corpus luteum structures in the ovarian tissue of PCOS rats after acupuncture intervention; E AMH secretion in the serum of PCOS rats after acupuncture intervention; F LH secretion in the serum of PCOS rats after acupuncture intervention; G FSH secretion in the serum of PCOS rats after acupuncture intervention; H T secretion in the serum of PCOS rats after acupuncture intervention; I E2 secretion in the serum of PCOS rats after acupuncture intervention. A-I, N = 6. These data are measured values, expressed as the mean ± standard deviation, * P < 0.05, *** P < 0. 0001 compared to the normal group; #P < 0.05, ###P < 0.0001 compared to the PCOS group, statistically analysis using one-way ANOVA and Tukey’s post hoc test. E2 stands for oestradiol, AMH stands for anti-Mullerian hormone, T stands for testosterone, FSH stands for follicle-stimulating hormone and LH stands for luteinizing hormone. 1: Normal group, 2: PCOS group, 3: PCOS + A group, 4: PCOS + SA group, 5: PCOS + W group

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