Table 1 TGF-β1 expression and clinicopathologic parameters of ICC
From: TGF-β1 expression is associated with invasion and metastasis of intrahepatic cholangiocarcinoma
TGF-β1 expression | p-value | ||
|---|---|---|---|
Gender | + | - | 0.654 |
Male (n = 38) | 18 | 20 | |
Female (n = 40) | 19 | 21 | |
Age | 0.453 | ||
<60 years(n = 31) | 17 | 14 | |
≥60 years(n = 47) | 20 | 27 | |
Stage | 0.097 | ||
I–II (n = 37) | 19 | 18 | |
III–IV (n = 41) | 18 | 23 | |
Size | 0.086 | ||
T1-T2 (n = 36) | 16 | 20 | |
T3-T4 (n = 42) | 21 | 21 | |
Lymph node metastasis | 0.003 | ||
Yes (n = 20) | 17 | 3 | |
No (n = 58) | 20 | 38 | |
Lymphovascular invasion | 0.045 | ||
Yes (n = 16) | 10 | 6 | |
No (n = 62) | 27 | 35 | |
Distant metastasis | 0.012 | ||
Yes (n = 8) | 8 | 0 | |
No (n = 70) | 29 | 41 | |
Histologic dedifferentiation | 0.145 | ||
Well differentiated (n = 42) | 21 | 21 | |
Moderately differentiated (n = 15) | 9 | 6 | |
Poorly differentiated (n = 21) | 7 | 14 | |
Tumour recurrence | 0.023 | ||
Yes(n = 47) | 26 | 21 | |
No(n = 31) | 11 | 20 | |