Figure 1
From: Methanol extract from Vietnamese Caesalpinia sappan induces apoptosis in HeLa cells
Induction of the DNA fragmentation in HeLa cells in vitro . HeLa cells were treated with MECS for 24 h (50, 20, 10 μg/mL), and for 36 and 48 h (50, 20 μg/mL). Total genomic DNA was extracted and resolved on a 1% agarose gel. Apoptotic DNA fragmentation was visualized by ethidium bromide staining. M, size marker; (−), mature cell; (−−), 0.1% DMSO-treated cells; (+), positive control treated with 2.5 μg/mL and (++), 5 μg/mL camptothecin.