Fig. 7

EA treatment increased the pain threshold and inhibited abnormal dendritic spine remodeling in rats with SNL, while CN04 reversed the effect of EA on the MWT and synaptic remodeling. A Schematic diagram of the experimental process. B Mechanical withdrawal threshold (MWT). n = 15. C Thermal withdrawal latency (TWL). n = 15. D Dendritic spines. Scale bars, 10 μm. E, F Five neurons were randomly selected from the dorsal horn of the spinal cord of each rat, and 20 to 30 dendritic spines were randomly selected from each neuron, and the lengths and head diameters of dendritic spines were measured. n = 4. G Number of spines per 10 μm. n = 4. H Number of thin spines per 10 μm. n = 4. I Number of mushroom spines per 10 μm. n = 4. ^$p < 0.05, ^$$p < 0.01 vs the SNL group, ^&&p < 0.01 vs. the SNL + EA group