Skip to main content
Fig. 5 | Biological Research

Fig. 5

From: Electroacupuncture inhibits dendritic spine remodeling through the srGAP3-Rac1 signaling pathway in rats with SNL

Fig. 5

EA promoted the expression of srGAP3 and inhibited the expression of Rac1-GTP in the spinal dorsal horns of rats with SNL, while the use of srGAP3 siRNA reversed the effects of EA. A–C Representative Western blots and quantitative analysis of srGAP3/GAPDH expression. n = 5. B–D Representative Western blots and quantitative analysis of Rac1-GTP/total Rac1 expression. n = 5. E–G Representative photos showing immunohistochemical staining of srGAP3 and active Rac1-GTP cells (The orange arrows show some representative srGAP3- and active Rac1-GTP-positive cells). Scale bars, 20 μm. F–H Number of srGAP3- and active Rac1-GTP-positive cells per field in the spinal dorsal horn. n = 4. Columns represent the mean ± SD. $$p < 0.01 vs. the SNL group, &&p < 0.01 vs. the SNL + EA group, *p < 0.05, **p < 0.01 vs the SNL + siNC group

Back to article page