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Fig. 4 | Biological Research

Fig. 4

From: Neuroprotective effects of the PPARβ/δ antagonist GSK0660 in in vitro and in vivo Parkinson’s disease models

Fig. 4

(A) Heatmap of overrepresented neuronal function pathways in DEG cluster 3. Heat map showing the clustering of samples by genes that significantly increased (red font) or decreased (green font) in 6-OHDA and 6-OHDA + GSK0660 vs. CTR cells. Red and green colors characterize relatively high and low log2 gene expression values, respectively. (B) Pie chart illustration of Panther Gene Ontology biological processes significantly overrepresented in this study. (C) Fold change indicates the ratio of the 6-OHDA vs. CTR, 6-OHDA + GSK0660 vs. CTR, 6-OHDA + GSK0660 vs. 6-OHDA groups

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