Fig. 1

Recovery of the splenic tissue architecture in the transplants. (A) Fragments of the spleen transplanted under the skin. (B) White pulp recovery; hematoxylin and eosin (H&E), objective lens 20, scale bar 100 μm. The proliferation intensity measurements:immunohistochemical visualization using anti-Ki67 antibodies (D) (FITC-conjugated secondary antibodies) and anti-PCNA antibodies (PE-conjugated secondary antibodies) (C), cell nuclei counterstained with DAPI, objective lens 40, scale bar 50 μm. The incision on day 7 was taken from the marginal zone of the graft in which cells with a dark nucleus first appeared. E. Ki67 index and PCNA index dynamics