Parameters | Groups | |||||
---|---|---|---|---|---|---|
Sham | NAFP | HFHS-8Â week | R-10 | R-20 | R-30 | |
Initial body weight, g | 160.5 ± 9.40 | 163.8 ± 10.23 | 162.7 ± 8.62 | 164.5 ± 6.83 | 161.7 ± 7.47 | 158.2 ± 7.41 |
Final body weight, g | 221.7 ± 9.33 | 451.8 ± 14.44* | 353.8 ± 10.23 | 421.8 ± 42.37 | 321.3 ± 31.14###a | 268.2 ± 33.37###ab |
TC (mg%) | 117.3 ± 15.31 | 273.7 ± 10.57* | 225.8 ± 8.04*## | 246.8 ± 9.96# | 206 ± 8.32###a | 131.2 ± 20.81###δab |
TG (mg%) | 50.23 ± 5.37 | 208.4 ± 23.91* | 143 ± 11.97*## | 131 ± 27.83### | 88.6 ± 13.73###δa | 61.24 ± 5.76###δa |
HDL-C (mg%) | 58.67 ± 4.1 | 26 ± 4.13* | 37 ± 2.76*## | 42 ± 2.48### | 45.8 ± 1.40###δ | 50.51 ± 3.89###δa |
LDL-C (mg%) | 44.18 ± 11.55 | 206 ± 9.13* | 160.8 ± 7.25*## | 181.9 ± 10.68##δ | 137.2 ± 14.57###δa | 80.11 ± 10.59###δab |
Glucose (mg%) | 101.3 ± 13.9 | 392 ± 39.01* | 279 ± 37.77*## | 260 ± 28.95### | 151.3 ± 7.94###δa | 125.6 ± 15.56###δa |
Insulin (µU/ml) | 5.07 ± 1.15 | 17.78 ± 1.09* | 15.24 ± 1.28*# | 14.85 ± 1.09## | 7.37 ± 1.71###δa | 6.037 ± 1.26###δa |
HOMA-IR | 1.38 ± 0.27 | 17.25 ± 2.46* | 10.75 ± 1.25*## | 9.547 ± 1.39### | 2.775 ± 0.75###δa | 1.85 ± 0.36###δa |
HbA1C% | 4.28 ± 0.94 | 11.32 ± 1.51* | 9.883 ± 1.22* | 8.6 ± 0.74## | 6.3 ± 0.6###δa | 5 ± 1.19###δa |
Lipase (U/L) | 350 ± 56.57 | 3868 ± 166.7* | 3613 ± 486* | 3478 ± 511 | 946.7 ± 133.5###δa | 595.5 ± 49.73###δa |
Amylase (U/L) | 983.7 ± 111.9 | 10,927 ± 1273* | 9245 ± 1504* | 9185 ± 1611# | 2931 ± 478.9###δa | 1190 ± 208.2###δab |