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Table 2 Body weight and blood parameters after 8 weeks of HFHS feeding

From: Prospective insight into the role of benzyl propylene glycoside as a modulator of the cGAS-STING signaling pathway in the management of nonalcoholic fatty pancreas animal model

 

Sham

HFHS-8 week

Initial body weight, g

160.3 ± 8.08

164.7 ± 8.96

Final body weight, g

190.8 ± 8.08

355.3 ± 9.33*

TC (mg%)

123.8 ± 11.68

227.3 ± 7.076*

TG (mg%)

49.07 ± 4.53

145.5 ± 13.6*

HDL (mg%)

59.33 ± 3.64

38.07 ± 2.84*

LDL (mg%)

54.27 ± 12.74

160.3 ± 7.86*

Glucose (mg%)

100.7 ± 11.07

280.3 ± 28.08*

Insulin (μU/ml)

4.907 ± 0.89

15.08 ± 1.16*

HOMA-IR

1.223 ± 0.26

10.42 ± 1.160*

HbA1C%

4.28 ± 0.80

9.94 ± 0.91*

Lipase (U/L)

354 ± 52.89

3523 ± 441.8*

Amylase (U/L)

1006 ± 94.21

9143 ± 1221*

  1. Values are mean ± SD; number = 15 rats/each group. Obtained from sample t-test
  2. *p < 0.001 vs Sham