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Table 2 Data for ART cycles in each cohort (donor-donor or donor-infertile). (A) Female physiological parameters and (B) embryo development

From: Sperm DNA integrity does play a crucial role for embryo development after ICSI, notably when good-quality oocytes from young donors are used

 

Donor-donor cohort

Donor-infertile cohort

P-value

Average ± SD

95% CI

Average ± SD

95% CI

A

 Age of female patient (years)

43.25 ± 4.019

[42.13 to 44.37]

36.91 ± 5.548

[35.45 to 38.37]

 < 0.0001

 Weight of female patient (kg)

62.5 ± 11.57

[59.28 to 65.72]

58.96 ± 17.3

[54.41 to 63.51]

0.418

 BMI of female patient

22.91 ± 3.549

[21.92 to 23.9]

21.14 ± 6.013

[19.56 to 22.72]

0.107

 Age of the woman who provides oocytes (years)

25.17 ± 4.057

[24.04 to 26.3]

36.91 ± 5.548

[35.45 to 38.37]

 < 0.0001

 Weight of the woman who provides oocytes (kg)

60.52 ± 9.948

[57.75 to 63.29]

58.96 ± 17.3

[54.41 to 63.51]

0.789

 BMI of the woman who provides oocytes

22.2 ± 3.138

[21.33 to 23.08]

21.14 ± 6.013

[19.56 to 22.72]

0.557

B

 Average number of MII oocytes recovered

16.15 ± 13.62

[10.76 to 21.54]

15.65 ± 11.65

[11.58 to 19.71]

0.865

 Average number of fertilized embryos

11.78 ± 9.79

[7.91 to 15.65]

11.21 ± 8.94

[8.09 to 14.33]

0.928

 Average number of blastocysts

7.26 ± 5.74

[4.99 to 9.53]

5.62 ± 5.25

[3.79 to 7.45]

0.138

 Average number of embryos transferred per donor

2.11 ± 1.85

[1.38 to 2.84]

2.09 ± 1.90

[1.43 to 2.75]

 > 0.999

 Fertilization rate (%)

75.76 ± 17.62

[68.92 to 82.59]

71.89 ± 14.77

[66.65 to 77.13]

0.275

 Blastocyst rate (%)

61.55 ± 19.65

[53.93 to 69.17]

50.38 ± 16.89

[44.39 to 56.37]

0.021a

 Blastocysts/MII oocytes injected (%)

48.27 ± 22.06

[39.71 to 56.82]

35.63 ± 12.57

[31.17 to 40.09]

0.006a

 Pregnancy/embryo transfer (%)

61.40% (35/57)

46.47% (33/71)

0.093

 Cumulative pregnancy/cycle (%)

71.42% (35/49)

57.89% (33/57)

0.147

 Live birth/embryo transfer (%)

56.14% (32/57)

38.02% (27/71)

0.041a

 Cumulative live birth/cycle (%)

65.30% (32/49)

47.37% (27/57)

0.064

 Miscarriage rate/pregnancy (%)

8.57% (3/35)

18.18% (6/33)

0.242

  1. Bold indicates statistically significant P-values
  2. A corresponds to female physiological parameters, B corresponds to embryo development parameters