Fig.3
From: Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy
Cellular and exosomal miR-1268a were upregulated in melanoma stem cells and transferred to melanoma cells. A, B The heat map and histogram of differentially expressed exosomal miRNAs in OL-SCs-EXO and OL-EXO. C, D Differentially expressed miRNAs in cells and exosomes of OL and OL-SCs were analyzed by RT-qPCR. E The expression level of miR-1268a in OL cells with and without OL-SCs-EXO treatment was detected by PCR. F OL-SCs exosomes with cy5-labeled miR-1268a were add to OL cells, co-cultured with PKH26-labeled exosomes for 6 h, 9 h, 12 h, respectively. Fluorescence signals were detected confocal fluorescence microscope. Scale bar, 20 μm. Data were expressed as the mean \(\pm\) SD, *p < 0.05, **p < 0.01, ***p < 0.001