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Table 2 Cycle characteristics and laboratory outcomes grouped by the vaccination status

From: Impact of inactivated SARS-CoV-2 vaccination on embryo ploidy: a retrospective cohort study of 133 PGT-A cycles in China

 

Vaccinated (n = 66)

Unvaccinated (n = 67)

P-value

Stimulation duration (days)

9.2 ± 1.3

9.5 ± 1.7

0.321

Total gonadotropin dose (IU)

2105.3 ± 476.7

2167.5 ± 563.9

0.764

LH level on trigger day (mIU/mL)

3.1 ± 2.4

2.7 ± 1.7

0.521

E2 level on trigger day (pg/mL)

2026.4 ± 1328.2

2005.7 ± 1150.2

0.721

P level on trigger day (ng/mL)

0.6 ± 0.7

0.5 ± 0.4

0.693

No. of ≥ 14 mm follicles on trigger day

8.2 ± 4.5

8.9 ± 4.1

0.269

No. of oocytes retrieved

12.2 ± 7.5

12.2 ± 6.9

0.948

No. of MII oocytes

9.3 ± 5.7

9.5 ± 5.5

0.878

No. of 2PN oocytes

8.2 ± 4.9

8.2 ± 5.2

0.923

No. of cleaved embryos

8.0 ± 4.9

8.0 ± 5.1

0.912

No. of usable blastocysts

3.8 ± 2.6

4.0 ± 3.4

0.841

No. of biopsied blastocysts

3.4 ± 2.0

3.7 ± 3.0

0.805

No. of aneuploid embryos

1.7 ± 1.4

1.6 ± 1.5

0.749

No. of mosaic embryos

0.7 ± 1.0

1.0 ± 1.3

0.222

No. of euploid embryos

1.0 ± 1.3

1.0 ± 1.3

0.954

Oocyte retrieval rate (%)

156.0 ± 70.6

135.5 ± 38.4

0.186

Mature oocyte rate (%)

79.3 ± 13.5

78.3 ± 13.8

0.883

Normal fertilization rate (%)

88.0 ± 14.7

86.3 ± 14.4

0.357

Cleavage rate (%)

97.9 ± 4.9

96.9 ± 9.8

0.886

Blastulation rate (%)

56.8 ± 20.9

58.2 ± 21.2

0.549

Aneuploidy rate (%)

57.4 ± 37.8

53.6 ± 35.3

0.563

Mosaicism rate (%)

19.4 ± 25.9

23.8 ± 28.5

0.406

Euploidy rate (%)

23.2 ± 24.6

22.6 ± 25.9

0.768

  1. Data are presented as mean ± standard deviation
  2. LH luteinizing hormone, E2 estradiol, P progesterone, MII metaphase II, 2PN two pronuclei