Table 1 Demographic features of the study groups
|  | Vaccinated (n = 66) | Unvaccinated (n = 67) | P-value |
|---|---|---|---|
Female age (years) | 37.7 ± 5.2 | 37.7 ± 4.5 | 0.867 |
Female BMI (kg/m2) | 21.9 ± 2.1 | 22.6 ± 2.7 | 0.127 |
Infertility duration (years) | 2.6 ± 2.5 | 3.7 ± 3.3 | 0.042 |
Infertility type, n (%) | Â | Â | 0.563 |
 Primary | 5 (7.6) | 7 (10.5) |  |
 Secondary | 61 (92.4) | 60 (89.6) |  |
Infertility diseases | |||
 Tubal factor, n (%) | 27 (40.9) | 25 (37.3) | 0.671 |
 Male factor, n (%) | 13 (19.7) | 9 (13.4) | 0.331 |
 Ovulatory dysfunction, n (%) | 4 (6.1) | 4 (6.0) | 1.000 |
 Diminished ovarian reserve, n (%) | 20 (30.3) | 27 (40.3) | 0.228 |
 Endometriosis, n (%) | 2 (3.0) | 4 (6.0) | 0.414 |
 Uterine factor, n (%) | 7 (10.6) | 9 (13.4) | 0.616 |
AMH (ng/mL) | 2.8 ± 1.8 | 3.1 ± 2.5 | 0.698 |
Antral follicle count | 11.4 ± 5.1 | 10.6 ± 5.0 | 0.604 |
Male age (years) | 39.8 ± 6.6 | 38.7 ± 6.0 | 0.394 |
Male BMI (kg/m2) | 24.6 ± 5.1 | 24.3 ± 5.0 | 0.508 |
Male vaccination status, n (%) |  |  |  < 0.001 |
 Unvaccinated | 14 (21.2) | 46 (68.7) |  |
 Partially vaccinated | 3 (4.6) | 4 (6.0) |  |
 Fully vaccinated | 49 (74.2) | 17 (25.4) |  |
Total semen volume (mL) | 2.7 ± 1.1 | 3.0 ± 1.0 | 0.074 |
Sperm concentration (106/mL) | 73 ± 48.8 | 67.4 ± 50.2 | 0.366 |
Progressive sperm motility (%) | 36.9 ± 14.8 | 33 ± 15.0 | 0.150 |
Normal sperm morphology (%) | 5.4 ± 1.4 | 5.5 ± 1.5 | 0.882 |
Ovarian stimulation protocol, n (%) | Â | Â | 0.997 |
 GnRH antagonist | 22 (33.3) | 22 (32.8) |  |
 MLSL | 26 (39.4) | 26 (38.8) |  |
 EFLL | 8 (12.1) | 9 (13.4) |  |
 PPOS | 10 (15.2) | 10 (14.9) |  |
Indication for PGT-A, n (%) | Â | Â | 0.919 |
 Advanced maternal age | 33 (50.0) | 31 (46.3) |  |
 Recurrent pregnancy loss | 24 (36.4) | 24 (35.8) |  |
 Recurrent implantation failure | 5 (7.6) | 7 (10.5) |  |
 Other | 4 (6.1) | 5 (7.5) |  |