Table 2 The variations in the expression of various genes in the mice liver and kidney treated with a different disparate concentration of zinc nanoparticles

Liver

Up-regulated genes

 iNOS

1.0^c

+ 1.4^c

+ 1.9^b

+ 2.7^a

0.13

 TNF-α

1.0^c

+ 1.6^c

+ 2.7^b

+ 3.9^a

0.14

Down-regulated genes

 SOD

1.0^c

− 1.5^c

− 2.1^b

− 2.9^a

0.10

 CAT

1.0^c

− 1.6^c

− 2.3^b

− 3.1^a

0.12

Kidney

Up-regulated genes

 iNOS

1.0^c

+ 1.1^c

+ 1.8^b

+ 2.3^a

0.15

 TNF-α

1.0^c

+ 1.3^c

+ 2.1^b

+ 3.4^a

0.11

Down-regulated genes

 SOD

1.0^c

− 1.4^c

− 1.7^b

− 1.9^a

0.10

 CAT

1.0^c

− 1.2^c

− 1.6^b

− 1.8^a

0.12