Fig. 6

Dietary K⁺ supplementation improves cardiac diastolic function in CHF rats. A Representative recording of left ventricle (LV) intraventricular pressure from one Sham rat, one CHF rat and one CHF+K⁺ rat (Upper panel). Lower panel shows ventilatory flows in each section. Note that end diastolic pressure (EDP) is modulated by the ventilatory cycle. B End diastolic pressure volume relationship assessed by single-beat PV-loop analysis during the expiratory and inspiratory phases of the breathing cycle. C Summary data of normalized EDP (nEDP) during inspiration and expiration. Note that the EDP was severely modulated by the ventilatory cycle in CHF rats and this was abolished by K⁺ diet supplementation. D Summary data showing percent changes in Δintraventricular pressures at Exp-Insp. Two-way ANOVA (C) and One-way ANOVA (D), followed by Holm Sidak posthoc. ^‡P < 0.05 vs. Insp; *P < 0.05 vs. Sham, #P < 0.05 vs CHF+K⁺ n = 5 rats per group