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Fig. 3 | Biological Research

Fig. 3

From: Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure

Fig. 3

Central chemoreflex drive is normalized by K+ supplementation in CHF rats. A Representative recording of tidal volume (VT) and respiratory frequency (Rf) during normoxia (FiO2 21%), hypercapnia (FiCO2 7%) and hypoxia (FiO2 10% in one Sham rat, one CHF rat and one CHF+K+ rat. B–C Summary data showing the magnitude (ΔVE, ml/min/100 g) and gain (ΔVE/%FiCO2) of the ventilatory response to hypercapnia (HCVR). Note that K+ supplementation totally restored normal HCVR in CHF rats. D–E Summary data showing the magnitude (ΔVE, ml/min/100 g) and gain (ΔVE/%FiO2) of the hypoxic ventilatory response (HVR). *P < 0.05 vs Sham, #P < 0.05 vs CHF+K+. Holm Sidak post hoc after One-Way ANOVA, n = 5 rats per group

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