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Fig. 2 | Biological Research

Fig. 2

From: Non-coding RNAs and chromatin: key epigenetic factors from spermatogenesis to transgenerational inheritance

Fig. 2

Environmental factors determining transgenerational epigenetic inheritance affecting offspring health. Sperm epigenome alterations due to environmental cues are transferred to the offspring. These inherited epigenetic signals can be useful biomarkers for disease diagnosis and treatment in preventive medicine for offspring. Paternal transgenerational epigenetic inheritance can be compensated by lifestyle and maternal nurture. Epigenetic analyses for sperm selection and in vitro culture enrichment with ncRNAs can be useful to improve fertility rates and embryo quality during ARTs

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