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Fig. 1 | Biological Research

Fig. 1

From: Diosmetin inhibits cell proliferation and promotes apoptosis through STAT3/c-Myc signaling pathway in human osteosarcoma cells

Fig. 1

Diosmetin inhibited the proliferation and cell viability of osteosarcoma Saos-2 and U2SO cells. A Chemical structure of diosmetin. B Representative images of cell colonies of Saos-2 and U2SO cells from six-well plates in which cells were treated with 0, 0.1, 0.3 and 0.9 μM of diosmetin (DIO) for 24 h by colony formation assay. C, D Quantification of colony number in diosmetin-treated Saos-2 (B) or U2SO (C) cells. E, F The cell survival rate of Saos-2 (D) and U2SO (E) cells which were treated with 0, 10, 30 and 90 μM of diosmetin respectively in 96-well plate were quantitatively analyzed by MTT assay. The results were shown as the mean ± SD of three independent experiments (n = 3, *P < 0.05, **P < 0.01 and ***P < 0.001 vs. DMSO control)

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