Fig. 4
From: DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice
DNMT1 knockdown repressed apoptosis and the levels of ROS in HG-treated HRCPs. HRCPs were transfected with si-DNMT1 or siRNA, and then treated with 30 mM glucose. A, C Flow cytometry was performed to estimate apoptosis of HRCPs. B, D The levels of ROS in HRCPs was detected by DCFH-DA fluorescent probe. *P < 0.05, **P < 0.01 vs. NG; &P < 0.05 vs. HG + siRNA