Fig. 6
From: Circulating miR-146a as a possible candidate biomarker in the indeterminate phase of Chagas disease
Interaction pathway of mmu-miR-21, mmu-miR-146b and mmu-miR-155 and target genes. These data reveal the interaction of 54 target genes for mmu-miR-21, 14 target genes for mmu-miR-146b and 28 target genes for mmu-miR-155. Red arrows indicate the genes related to virulence by T. cruzi and host immune response. CAMP Responsive Element Binding Protein 1(Creb1), Mitogen-Activated Protein Kinase Kinase Kinase 1 (Map3k1), IQ Motif Containing GTPase Activating Protein 1(Iqgap1), BCL2 Apoptosis Regulator (Bcl2), SMAD Family Member 5 (Smad5), Nuclear factor of activated T cells 1 (Nfatc1), Glicogen Synthase Kinase 3 beta (Gsk3b), Nuclear factor of activated T cells 5 (Nfat5) and Insulin like grown factor 1 receptor (Igf1r)