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Table 2 Clinical data for the GDM patients and normal controls in the validation cohort

From: The role of circular RNA circ_0008285 in gestational diabetes mellitus by regulating the biological functions of trophoblasts

Characteristics GDM(n = 57) HC(n = 63) p-value
Maternal age (year) 33.54 ± 4.62 31.90 ± 3.85 0.04
Gestational weeks of delivery 38.30 ± 8.14 38.84 ± 2.94 0.77
Pre-pregnancy BMI (kg/m2) 26.03 ± 1.98 26.18 ± 1.63 0.11
Fasting glucose (mmol/L) 4.45 ±  0.54 3.99 ± 0.34  < 0.001
1 h plasma glucose (mmol/L) 9.67 ± 1.27 7.40 ± 1.19  < 0.001
2 h plasma glucose (mmol/L) 8.62 ± 1.11 6.04 ± 1.17  < 0.001
GHBA1c (%) 5.40 ± 0.47 5.25 ± 0.47 0.08
Neonatal birth weight (Kg) 2.96 ± 0.58 3.13 ± 0.50 0.08
Hemoglobin (g/L) 118.10 ± 13.88 117.40 ± 12.73 0.79
ALT(U/L) 14.40 ± 6.32 15.22 ± 6.56 0.49
AST(U/L) 21.09 ± 4.69 20.43 ± 4.39 0.43
Triglycerides (mmol/L) 3.65 ± 1.44 3.69 ± 2.39 0.92
Total cholesterol (mmol/L) 6.39 ± 1.17 6.44 ± 1.02 0.81
HDL-C (mmol/L) 1.81 ± 0.32 1.80 ± 0.36 0.94
LDL-C (mmol/L) 3.65 ± 0.78 368.00 ± 0.66 0.85
TBA (umol/L) 3.44 ± 3.69 3.19 ± 1.80 0.63
Abortion history
 Yes 29 (50.88%) 15 (23.81%) 0.02
 No 28 (29.12%) 48 (76.19%)
Gestational hypertension (yes/total)
 Yes 7 (12.28%) 1 (1.59%) 0.02
 No 50 (87.72%) 62 (98.41%)
Mode of delivery
 Eutocous 30 (52.63%) 46 (73.02%) 0.02
 Anesthesia operation 27 (47.37%) 17 (26.98%)
Fetal distress
 Yes 18 (31.58%) 14 (22.22%) 0.25
 No 39 (68.42%) 49 (77.78%)
Shoulder dystocia
 Yes 1 (1.75%) 0 (0.00%) 0.29
 No 56 (98.25%) 63 (100.00%)
Preterm birth
 Yes 4 (7.55%) 7 (11.11%) 0.43
 No 53 (92.45%) 56 (88.89%)
Postpartum bleeding
 Yes 5 (8.77%) 5 (7.94%) 0.87
 No 52 (91.23%) 58 (92.06%)