| |
Cases
|
Controls
|
OR (95% CI)a
|
P-valuea
|
OR (95% CI)b
|
P
b
|
|---|
|
All subjects
|
|
All samples
|
297c
| |
1.29 (0.96–1.72)
|
0.092
|
1.29 (0.92–1.72)
|
0.095
|
|
Intestinal-type
|
157
| |
1.08 (1.08–2.14)
|
0.016
|
1.55 (1.10–2.20)
|
0.013
|
|
Diffuse-type
|
140
| |
1.07 (0.74–1.55)
|
0.732
|
1.29 (0.96–1.72)
|
0.095
|
|
H. pylori-positive
|
|
All samples
|
102
|
102
|
1.88 (1.08–3.24)
|
0.02
|
1.70 (0.96–3.00)
|
0.07
|
|
Intestinal-type
|
50
|
102
|
2.69
(1.41–5.13)
|
2.6 × 10
−3
|
2.50 (1.26–4.96)
|
0.01
|
|
Diffuse-type
|
52
|
102
|
1.26 (0.63–2.52)
|
0.51
|
1.23 (0.61–2.48)
|
0.56
|
|
H. pylori cag PAI-positive
|
|
All samples
|
87
|
43
|
4.90
(1.80–13.36)
|
1.9 × 10
−3
|
4.32 (1.57–11.89)
|
4.6 × 10−3
|
|
Intestinal-type
|
42
|
43
|
7.16
(2.40–21.33)
|
4.1 × 10
−4
|
6.77
(2.18–21.02)
|
9.5 × 10
−4
|
|
Diffuse-type
|
45
|
43
|
3.39 (1.13–10.10)
|
0.03
|
3.20 (1.06–9.67)
|
0.04
|
- aUnadjusted
- bAdjusted for sex, principal component (PC)1 and PC2. OR: odds ratio. 95% CI: 95 % confidence interval. Statistically significant results are shown in bold (Significance level after Bonferroni’s correction < 2.9 × 10−3)
- cTwo cases with no-defined adenocarcinoma
