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Table 1 Association of NOD1 rs2075820 with gastric cancer

From: NOD1 rs2075820 (p.E266K) polymorphism is associated with gastric cancer among individuals infected with cagPAI-positive H. pylori

  Cases Controls OR (95% CI)a P-valuea OR (95% CI)b P b
All subjects
 All samples 297c   1.29 (0.96–1.72) 0.092 1.29 (0.92–1.72) 0.095
 Intestinal-type 157   1.08 (1.08–2.14) 0.016 1.55 (1.10–2.20) 0.013
 Diffuse-type 140   1.07 (0.74–1.55) 0.732 1.29 (0.96–1.72) 0.095
H. pylori-positive
 All samples 102 102 1.88 (1.08–3.24) 0.02 1.70 (0.96–3.00) 0.07
 Intestinal-type 50 102 2.69 (1.41–5.13) 2.6 × 10 −3 2.50 (1.26–4.96) 0.01
 Diffuse-type 52 102 1.26 (0.63–2.52) 0.51 1.23 (0.61–2.48) 0.56
H. pylori cag PAI-positive
 All samples 87 43 4.90  (1.80–13.36) 1.9 × 10 −3 4.32 (1.57–11.89) 4.6 × 10−3
 Intestinal-type 42 43 7.16 (2.40–21.33) 4.1 × 10 −4 6.77 (2.18–21.02) 9.5 × 10 −4
 Diffuse-type 45 43 3.39 (1.13–10.10) 0.03 3.20 (1.06–9.67) 0.04
  1. aUnadjusted
  2. bAdjusted for sex, principal component (PC)1 and PC2. OR: odds ratio. 95% CI: 95 % confidence interval. Statistically significant results are shown in bold (Significance level after Bonferroni’s correction < 2.9 × 10−3)
  3. cTwo cases with no-defined adenocarcinoma