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Fig. 3 | Biological Research

Fig. 3

From: CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis

Fig. 3

CircRSF1 directly targeted miR-135b-5p in HUVECs. a The predicted binding sites of miR-135b-5p to the circRSF1 sequences using circbank. bd Dual luciferase reporter assay (b), RIP assay (c, d) and pull down (e) determined that miR-135b-5p was a target miRNA of circRSF1 in HUVECs. f qRT-PCR was used to detect the expression of miR-135b-5p in si-NC and si-circRSF1 groups, vector and circRSF1 groups (g), control and ox-LDL groups h in HUVECs. Each experiment was performed in triplicate *p < 0.05

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