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Fig. 1 | Biological Research

Fig. 1

From: CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis

Fig. 1

Oxidative (ox)-LDL(Ox-LDL) inhibited circRSF1 expression in HUVECs. a The graph of genomic loci of RSF1 gene and circRSF1. b The effect of actinomycin D (ActD) on cells was detected by qRT-PCR, and the abundances of circRSF1 and RSF1 mRNA were detected at specified time points. c RNase R digestion test was used to test the stability of circRSF1. After RNase R treatment, the expression of circRSF1 was more stable than RSF1 mRNA. d The expression of circRSF1 in nuclear and cytoplasmic of HUVECs e the expression of circRSF1 was detected in Control and ox-LDL of HUVECs. Each experiment was performed in triplicate *p < 0.05

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Biological Research

ISSN: 0717-6287

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