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Fig. 3 | Biological Research

Fig. 3

From: Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment

Fig. 3

Knockdown of linc-OIP5 in MDA-MB-231 cells suppressed the proliferation and migration of co-cultured HUVECs in vitro. a Relative expression levels of linc-OIP5 were detected after MDA-MB-231 cells transfected with linc-OIP5 siRNAs. b Knockdown of linc-OIP5 significantly suppressed HUVECs proliferative capacity by CCK-8 assays. c Migration ability of the co-cultured HUVECs after linc-OIP5 knockdown reduced appreciably through wound healing assays. Fold changes were obtained by normalizing against control group. Magnification×40. NS no statistical difference, *P < 0.05, ** P < 0.01

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