Fig. 7
From: Improvement of endothelial function by Gunnera tinctoria extract with antioxidant properties
Blockade of contractile response to U46619 induced by G. tinctoria extract. Isometric tension of rings of human chorionic vein vessels incubated (37 °C, 95% O2/5% CO2) in absence (black circles, labeled C) or presence of 200 μg/L G. tinctoria extract (blue squares, labeled as GT) and previously exposed to 0.1 μM U46619 (thromboxane A2 analog). a The changes in isometric tension are shown after adjustment and equilibration of vessels to 1.0 g. The addition of KCl solution (90 mM), physiological buffer (Wash), U46619 and G. tinctoria are indicated with arrows. b The isometric changes after incubation with G. tinctoria (section highlighted in a) is shown in detail. U46619 was not removed. The slopes for U46619 constriction, calculated from linear regression, are 0.062 ± 0.002 (g/min) and 0.013 ± 0.002 (g/min) for control and G. tinctoria, respectively. Values are mean ± SEM, n = 5. *p < 0.05 versus control (C)