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Fig. 2 | Biological Research

Fig. 2

From: Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance, mitochondrial dysfunction and oxidative stress

Fig. 2

EA intervention alleviated PCOS-like symptoms via regulating SREBP1. a The protein level of SREBP1 in ovarian tissues from different groups was evaluated by Western blotting. b The pathological changes in ovarian tissues were observed by HE staining (magnification, 100 ×). Scar bar = 200 μm. The serum levels of FSH (c), LH (d), and testosterone (f) were determined by ELISA kits. e The ratio of LH/FSH was calculated and shown. The protein levels of CYP17 (g) and CYP19 (h) in ovarian tissues were detected by Western blotting. The mRNA expression of CYP17 (i) and CYP19 (j) in ovarian tissues was assessed by real-time PCR. All data are presented as mean ± standard deviation (n = 6). *P < 0.05, **P < 0.01, ***P < 0.001 versus the indicated group

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