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Fig. 6 | Biological Research

Fig. 6

From: Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice

Fig. 6

The effect of daphnetin on skin lesion in IMQ-induced psoriasis-like mouse model. a The macroscopic appearance of mouse back skin on day 8. b Erythema and (c) scaling was scored on days 0, 2, 4, and 7 based on the PASI. d H&E staining of the mouse skin. Bar, 100 μm. e Epidermal thickness was calculated by Image-pro Plus 6.0 software. ***P < 0.001. f qRT-PCR was performed to measure the expression of KRT6 in skin lesion. GAPDH served as an internal reference. *P < 0.05. **P < 0.01. g Dermal cellular infiltrates were quantitated with H&E staining images. *P < 0.05. ***P < 0.001

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