Fig. 1

Analyses of body composition and food intake of Arid5b^+/+ and Arid5b^−/− mice. a Arid5b expression in GC muscle. Total RNA was isolated from GC muscle and qRT-PCR analysis was performed. Gene expression was normalized to Rpl13a mRNA expression. Arid5b^+/+, n = 7; Arid5b^−/−, n = 3. *,  P < 0.05. b, c Absolute muscle weights in Arid5b^+/+ and Arid5b^−/− mice. GC, QC, SoL and EDL muscles were dissected from male Arid5b^+/+ mice and Arid5b^−/− mice, and the weight was measured. d, e Normalized skeletal muscle weight was determined by taking the ratio of each skeletal muscle weight to the body weight of the mice. Results are presented as the means ± SD. *, P < 0.05; ***, P < 0.001. GC and QC: Arid5b^+/+ mice, n = 18; Arid5b^−/− mice, n = 9. SoL and EDL: Arid5b^+/+ mice, n = 3; Arid5b^−/− mice, n = 4. f Absolute food intake and normalized food intake relative to body weight (BW) in each genotype (n = 5 per group). Data are presented as the means ± SD. *, P < 0.05; **, P < 0.01 (dark period vs light period)