Fig. 6

MATR3 expression is inversely correlated with the aggressiveness of breast tumors. a RNA-sequencing datasets from TCGA were analyzed and MATR3 mRNA levels were compared between primary breast tumors and normal breast tissues. n = 1097 (primary breast tumors) and 114 (normal breast tissues). b RNA-sequencing datasets at bc-GenExMiner were analyzed to compare MATR3 mRNA levels between basal-like (BL) and triple-negative breast cancer (TNBC) and not-BL and not-TNBC. n = 267 (BL & TNBC) and 3689 (not-BL & not-TNBC). RNA-sequencing datasets at bc-GenExMiner were analyzed to compare MATR3 mRNA levels between hormone receptor (c, estrogen receptor; d, progesterone receptor)-negative and -positive breast cancers. n = 551 (ER-negative), 3911 (ER-positive), 828 (PR-negative) and 3498 (PR-positive). e RNA-sequencing datasets at bc-GenExMiner were analyzed to compare MATR3 mRNA levels between human epidermal growth factor receptor 2 (HER2)-negative and -positive breast cancers. n = 3582 (HER2-negative) and 661 (HER2-positive). Statistical significance in a was determined by an unpaired t-test. Error bars are s.e.m. The boxes in b-e show the median and interquartile range, and the whiskers show the minimum and maximum. Statistical significance in b-e was determined by pre-set analytic methods of the online tool