Fig. 2
From: Palmatine ameliorates high fat diet induced impaired glucose tolerance
Effect of PAL on the insulin resistance and β-cell mass in high fat diet induced rats. aThe blood insulin levels of three groups. b The HOMA-IR in three groups. c The β cells mass in each group determined by immunohistochemical staining. Scale bar: 50 μm. d Quantification of the β cell mass. e Cell apoptosis in β cells determined by TUNEL/insulin immunofluorescent staining. Scale bar: 50 μm. f Quantification of TUNEL-postive β cells. Values are expressed as mean ± SD. n = 6. Compared with control group: #P < 0.05, ##P < 0.01, ### P < 0.001, #### P < 0.0001; Compared with IGT group, *P < 0.05, **P < 0.01, *** P < 0.001, **** P < 0.0001