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Fig. 2 | Biological Research

Fig. 2

From: LncRNA SNHG14 promotes OGD/R-induced neuron injury by inducing excessive mitophagy via miR-182-5p/BINP3 axis in HT22 mouse hippocampal neuronal cells

Fig. 2

SNHG14 overexpression promotes mitophagy of OGD/R-induced HT22 cells. HT22 cells were transfected with pcDNA3.1-SNHG14, pcDNA3.1-NC, si-SNHG14 or si-Ctrl. Then, the modified HT22 cells were subjected to OGD/R treatment. The expression of PINK-1, Parkin, BNIP3, Beclin-1, LC3I and LC3II in the modified HT22 cells was examined by WB. (*P < 0.05, **P < 0.01, versus Vector; #P < 0.05, ##P < 0.01, versus si-Ctrl)

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