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Fig. 9 | Biological Research

Fig. 9

From: Hypoxia inducible factor-1 (HIF-1α) reduced inflammation in spinal cord injury via miR-380-3p/ NLRP3 by Circ 0001723

Fig. 9

The inactivation of NLRP3 reduced the anti-inflammation effects of anti-Circ 0001723 on inflammation in vitro model of SCI. NLRP3 and Caspase-1 protein expression by western blot analysis (a and b) and statistical analysis (c), TNF-α (d), IL-1β (e), IL-6 (f) and IL-18 (g). Negative, negative control group; 0001723 inhibitor, down-regulation of Circ 0001723 group; 0001723 inhibitor + si-NLRP3, down-regulation of Circ 0001723 and NLRP3 group. **p < 0.01 compared with negative control group, ##p < 0.01 compared with down-regulation of Circ 0001723 group.

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Biological Research

ISSN: 0717-6287

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