Fig. 2

Edaravone inhibited IR-induced apoptosis in kidney tubular epithelial cells. a The terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) was performed to detect the apoptotic nuclei. b The left bar graph showed the apoptosis rate in each group and the right bar graph showed the apoptosis rate normalized by the sham data in each group. c The up image is showed the changes of apoptotic proteins caspase-3 in each group were detected by western blot and the below bar graph showed the level of caspase-3 normalized by the sham data in each group. Data are represented as mean ± SEM (n = 10 per group) *P < 0.05, **P < 0.01, ***P < 0.001 vs. sham; ^#P < 0.05, ^###P < 0.001 vs. IR