Fig. 5

Treatment of EGFP hiPSC-derived myogenic progenitors reduced the ratio of central nuclei myofibers (CNFs) in mdx mice. a H&E staining showed representative images of TA muscles in negative control mdx mice (left), PBS-injected right TA muscles (middle), and cell-transplanted left TA muscles (right) at 8 weeks after intramuscular transplantation. b H&E staining showed representative images of TA muscles in mdx mice received PBS (left) and cells (right) at 8 weeks after intravenous transplantation. c Quantitative analysis indicated the percentage of CNFs for each group at 8 weeks after intramuscular transplantation. d Quantitative analysis indicated the percentage of CNFs for each group at 8 weeks after intravenous transplantation. 5 random sections for each muscle were examined. **P < 0.01, ***P < 0.001. Scale bars = 400 μm