TY - JOUR AU - He, Ruojie AU - Li, Huan AU - Wang, Liang AU - Li, Yaqin AU - Zhang, Yu AU - Chen, Menglong AU - Zhu, Yuling AU - Zhang, Cheng PY - 2020 DA - 2020/05/19 TI - Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy JO - Biological Research SP - 22 VL - 53 IS - 1 AB - Duchenne muscular dystrophy (DMD) is a devastating genetic muscular disorder with no effective treatment that is caused by the loss of dystrophin. Human induced pluripotent stem cells (hiPSCs) offer a promising unlimited resource for cell-based therapies of muscular dystrophy. However, their clinical applications are hindered by inefficient myogenic differentiation, and moreover, the engraftment of non-transgene hiPSC-derived myogenic progenitors has not been examined in the mdx mouse model of DMD. SN - 0717-6287 UR - https://doi.org/10.1186/s40659-020-00288-1 DO - 10.1186/s40659-020-00288-1 ID - He2020 ER -