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Fig. 3 | Biological Research

Fig. 3

From: Knockdown of long non-coding RNA HOTAIR reverses cisplatin resistance of ovarian cancer cells through inhibiting miR-138-5p-regulated EZH2 and SIRT1

Fig. 3

Upregulation of miR-138-5p enhanced chemosensitivity of DDP-resistant ovarian cancer cells to DDP. a Verification of overexpression of miR-138-5p by real-time PCR assay, U6 were used as an internal control. b The effect of different concentrations of DDP on cell viability in SKOV3/DDP and A2780/DDP cells with or without forced overexpression of miR-138-5p was assessed by MTT assay, and the IC50 value was obtained. Data were presented as mean ± SD. * p < 0.05

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