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Fig. 2 | Biological Research

Fig. 2

From: Knockdown of long non-coding RNA HOTAIR reverses cisplatin resistance of ovarian cancer cells through inhibiting miR-138-5p-regulated EZH2 and SIRT1

Fig. 2

Knockdown of HOTAIR increased miR-138-5p expression in DDP-resistant ovarian cancer cells. a Downregulation of HOTAIR by two different small interfering RNAs. b The expression of miR-138-5p in DDP-resistant ovarian cancer cells after silencing of HOTAIR was assessed by real-time PCR, beta-actin and U6 were used as an internal control for HOTAIR and miR-138-5p detection, respectively. c Dual-luciferase assay was used to verify the direct binding of miR-138-5p and HOTAIR. Data were presented as mean ± SD. * p < 0.05

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Biological Research

ISSN: 0717-6287

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