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Fig. 6 | Biological Research

Fig. 6

From: LncRNA LINC00483 promotes gastric cancer development through regulating MAPK1 expression by sponging miR-490-3p

Fig. 6

Knockdown of LINC00483 decreases tumor growth in gastric cancer xenograft model. a Tumor volume was measured every week. b Tumor weight was detected at the end. c qRT-PCR assay detected the expression levels of LINC00483, miR-490-3p and MAPK1 in tumor tissues. d Western blot assay examined the protein levels of MAPK1, c-Myc, Bax and MMP-9 in tumor tissues. sh-LINC00483: xenograft tumor formed using MGC-803 cells with LINC00483 knockdown using shRNA; sh-NC: xenograft tumor formed using MGC-803 cells with transfection of shRNA negative control. *P < 0.05 compared with sh-NC group

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