Skip to main content

Table 1 Schematic representation of tight junction-related protein affected by miRNAs

From: Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells

miRNA Targets miRNA Targets
hsa-miR-223 CLDN8 [14] hsa-miR-212 CLDN, JAMC, TJP1 [41, 42]
hsa-miR-21 OCLN, CLDN1, CLDN5 [43,44,45, 39] hsa-miR-29a CLDN1 [46]
hsa-miR-16 ZO-1, OCLN, CLDN2 [47, 48] hsa-miR-18a ZO-1, OCLN, CLDN5 [49, 50]
hsa-miR-23a ZO-1 [40] hsa-miR-146a CLDN1, OCLN, JAMA [51]
hsa-miR-320a JAMA [52] hsa-miR-34c-5p ZO-1, OCLN [53]
hsa-miR-191 ZO-1 [54] hsa-miR-34c-3p ZO-1, OCLN [53]
hsa-miR-99b CLDN11 [55] hsa-miR-181a ZO-1, OCLN, CLDN5 [28]
hsa-let-7b OCLN, ZO-1 [56] hsa-miR-122 ZO-1, ZO-3, OCLN [57, 58]
hsa-miR-132 CLDN1, JAM3, TJP1 [41, 59] hsa-miR-143 ZO-1, ZO-3, OCLN, CLDN5 [60, 61]
hsa-miR-101 VE-cadherin [62] hsa-miR-21-3p OCLN, CLDN5, ZO-1 [63]
hsa-miR-15a ZO-1, OCLN [48] hsa-miR-125b CLDN2 [47]
hsa-miR-210 OCLN [64] hsa-miR-200b OCLN, CLDN5, CLDN1, ZO-1 [65, 66]
hsa-miR-34a ZO-1, OCLN, CLDN5 [67] hsa-miR-96 ZO-1 [68]
hsa-miR-150 CLDN5 [69] hsa-miR-429 OCLN [70]
hsa-miR-107 ZO-1, OCLN, CLDN5 [71] hsa-miR-30a CLDN1, CLDN2, CLDN3 [72]
hsa-miR-144 OCLN, ZO-1, CLDN5 [73]   
  1. The miRNAs detected in MCs-derived exosomes have been reported to target different tight junction proteins. The enrichment of miRNA CT value was listed in Additional file 1: Table S1