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Fig. 4 | Biological Research

Fig. 4

From: LncRNA LINC00460 promotes the papillary thyroid cancer progression by regulating the LINC00460/miR-485-5p/Raf1 axis

Fig. 4

Inhibition of miR-485-5p reversed the effects of LINC00460 knockdown in PTC cells. ai TPC1 and BCPAP cells were transfected with si-NC, si-LINC00460#1, si-LINC00460#1 + anti-miR-NC and si-LINC00460#1 + anti-miR-485-5p, respectively. a The expression of miR-485-5p was detected by qRT-PCR. b, c Cell proliferation was detected by CCK-8 assay at 0 h, 24 h, 48 h and 72 h after transfection. d The migrated cells were measured by transwell assay. e The invaded capacity was evaluated by transwell assay after transfection. fi EMT-related proteins (MMP9, E-cadherin, N-Cadherin and Vimentin) expression was detected by western blot. **P < 0.01

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