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Fig. 3 | Biological Research

Fig. 3

From: RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway

Fig. 3

Overexpression of SCD1 inhibited colon cancer cells proliferation in vitro. a LoVo and HCT-116 were transfected with vector control and SCD1 for 48 h, and detected the transfection efficacy by western blot. Data are expressed as mean ± SEM, n = 3, *P < 0.05. b Growth curves of LoVo and HCT-116 cells after transfection with SCD1 and vector control were determined by CCK-8 assays. Data are expressed as mean ± SEM, n = 3, *P < 0.05. c Cell cycle assay showed that SCD1 caused G2/M arrest of LoVo (8.7–20.4%) and HCT-116 (6.5–17.9%) cells. Data are expressed as mean ± SEM, n = 3, *P < 0.05

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