Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells

Biological Research

Table 1 Number of revertants in four different Salmonella typhimurium strains incubated with increasing concentrations of etanorin

Treatment	Number of histidine + revertants
	TA98		TA100		TA102		TA104
	S9−	S9+	S9−	S9+	S9−	S9+	S9−	S9+
Spontaneous revertions	30 ± 2	22 ± 4	40 ± 7	38 ± 6	345 ± 43	328 ± 28	315 ± 23	365 ± 48
DMSO	26 ± 6	24 ± 3	42 ± 3	39 ± 7	305 ± 32	324 ± 35	363 ± 32	321 ± 24
Standard mutagens^a	87 ± 14	968 ± 192	320 ± 66	790 ± 59	1416 ± 34	4848 ± 113	2069 ± 125	4625 ± 167
E 0.125 µg/plate	26 ± 6	29 ± 2	52 ± 5	56 ± 6	352 ± 25	359 ± 9	384 ± 46	361 ± 52
E 12.5 µg/plate	26 ± 4	27 ± 1	50 ± 4	40 ± 3	306 ± 19	352 ± 21	325 ± 41	374 ± 28
E 125 µg/plate	22 ± 6	22 ± 2	47 ± 9	40 ± 6	296 ± 47	340 ± 21	359 ± 36	346 ± 44

^aStandard mutagens: 4-nitroquinoline-N-oxide for TA98, methylmethanesulfonate for TA100 and TA102 and methylglyoxal for TA104

ISSN: 0717-6287